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Adenoid cystic carcinoma of base of tongue: Rare tumor in rare location treated with upfront curative radiotherapy

1 Department of Radiation Oncology, Army Hospital Research and Referral, New Delhi, India
2 Department of ENT, Army Hospital Research and Referral, New Delhi, India
3 Department of Radiology, Army Hospital Research and Referral, New Delhi, India

Correspondence Address:
Abhishek Purkayastha,
Department of Radiation Oncology, Army Hospital, Research and Referral, Dhaula Kuan, Delhi Cantt, New Delhi - 110 010
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0976-6944.194377

Adenoid cystic carcinoma (ACC) is a rare variant of adenocarcinoma accounting for <1% of all head and neck malignancies. They arise mostly from minor salivary glands of the upper aero-digestive tract and are treated mainly by surgical resection. Hard palate is the most common site while base of tongue (BOT) locations are extremely rare. We hereby report a case of ACC of BOT in a 65-year-old male who presented with dysphagia of 8 months duration. The patient was deemed a nonsurgical candidate due to the location of the tumor and morbidity of surgery. We treated him with radiotherapy (RT) after a thorough histological diagnosis. The patient responded well to RT with complete remission of the tumor and significant symptomatic relief. He has been started on oral imatinib mesylate in view of CD-117 positivity. At present, on regular follow-up for over a year without any evidence of local recurrence or distant metastasis.

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