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Castleman's disease

1 Department of Oral Pathology and Microbiology, KVG Dental College and Hospital, Sullia, Dakshina Kannada, Karnataka, India
2 Department of Oral and Maxillofacial Surgery, Government General Hospital, Puttur, Karnataka, India

Correspondence Address:
Harishchandra Rai,
Department of Oral Pathology and Microbiology, KVG Dental College and Hospital, Sullia - 574 237, Dakshina Kannada, Karnataka
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0976-6944.187438

Castleman's disease (CD) is a rare atypical lymphoproliferative disorder characterized by enlarged hyperplastic lymph nodes with striking vascular proliferations. CD is categorized as being either localized or disseminated and further subdivided into hyaline vascular (HV), plasma cell, or mixed histopathological patterns. Here, we report a case of CD with a solitary asymptomatic HV mass in the right submandibular space. In addition, we discuss the pathogenesis, clinical features, and reported comorbidities of uni- and multi-centric CD and evaluate effective treatment strategies. A brief review of the literature for the various facets of this condition from published case reports is also provided.

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