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EDITORIAL
Year : 2013  |  Volume : 4  |  Issue : 3  |  Page : 103-104

Discovering the unexpected sources…!!!


Department of Periodontology, National Dental College and Hospital, Dera Bassi, Punjab, India

Date of Web Publication12-Dec-2013

Correspondence Address:
Ranjan Malhotra
Department of Periodontology, National Dental College and Hospital, Dera Bassi, Punjab
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0976-6944.122950

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How to cite this article:
Malhotra R. Discovering the unexpected sources…!!! . Indian J Oral Sci 2013;4:103-4

How to cite this URL:
Malhotra R. Discovering the unexpected sources…!!! . Indian J Oral Sci [serial online] 2013 [cited 2019 Nov 20];4:103-4. Available from: http://www.indjos.com/text.asp?2013/4/3/103/122950

Ever wondered, if there could be something, which could cut your risk of heart disease, keep you fitter and slow, or reverse the age clock and not to forget protect your pearly smile?

A paradox of being alive is that, whereas all of us need oxygen for our existence, but which being a reactive molecule does damage the living cells by producing reactive oxygen species. [1] To fight back, nature has blessed us with a complex network of antioxidant metabolites and enzymes that work together to prevent oxidative damage to our vital cellular components such as deoxyribonucleic acid, proteins and lipids. [2],[3] Antioxidants, either prevent these reactive species from being formed, or remove them before they can damage vital components of the cell, [1] are occupying not only a large volume in the literature, but also going global on internet and other social media outlets these days. However, reactive oxygen species also have useful cellular functions, e.g., redox signaling, that might help killing externous/infectious molecules. Thus, the function of antioxidant systems is not to remove oxidants entirely, but instead to keep a tap, maintaining them at an optimum level.

This state of balance is really an important requisite for achieving and maintaining a good oral as well as systemic health. [4] Factors such as pollutants, alcohol, nicotine, hydrogen peroxide, and dental compounds and procedures can disturb the balance of oxidants in oral tissues, causing oxidative stress. Antioxidants can help to offset the imbalance. Continuous efforts are focused, to identify such natural reducing substances, in our day to day life which could prevent such detrimental oxidative reactions and enhance our general health and quality of life. Several decades of dietary research findings suggested that consuming greater amounts of antioxidant-rich foods might help to protect against diseases. It has been suggested that the negative effects of nicotine in smokers could be reversed by antioxidants and the use of specific antioxidants in the proper combination can provide natural protection from environmental and inherent free-radical exposure.

Though a healthy, varied diet rich in fruits and vegetables, whole grains, and nuts is an excellent source of antioxidants, but these may be supplied by other external means as well. [4] Most recently, dental manufacturers and distributors have worked on introducing antioxidant supplements into toothpastes, mouth rinses/mouthwashes, lozenges, fluoride gels and dentifrices, oral sprays, breath fresheners, and other dental products for the control of gingival and periodontal diseases. The rapidly advancing field of dental pharmacotherapeutics has paved the way for the development of a wide array of antioxidants that have beneficial clinical effects. [5] However, it is important to understand, given the inherent unstable nature of antioxidants, that simply adding an antioxidant to an oral preparation may not be an effective treatment. [6] Further research is critical to discover novel portals, formulations, vehicles to deliver antioxidants and to formulate regulations for their usage, efficacy and safety to be utilized as a combination or a standalone therapy for oral disease prevention and treatment.

Until then, upgrade your health quotient by adopting a healthy life-style with regular physical exercise and a very colorful diet, filled with these super food elements "antioxidants"…!!!

 
  References Top

1.Davies KJ. Oxidative stress: The paradox of aerobic life. Biochem Soc Symp 1995;61:1-31.  Back to cited text no. 1
    
2.Vertuani S, Angusti A, Manfredini S. The antioxidants and pro-antioxidants network: An overview. Curr Pharm Des 2004;10:1677-94.  Back to cited text no. 2
    
3.Sies H. Oxidative stress: Oxidants and antioxidants. Exp Physiol 1997;82:291-5.  Back to cited text no. 3
    
4.Available from: http://www.dentalantioxidants.com/antioxidants-and-oral-heath. [Last accessed on 2013 Nov 28].  Back to cited text no. 4
    
5.Carnelio S, Khan SA, Rodrigues G. Definite, probable or dubious: Antioxidants trilogy in clinical dentistry. Br Dent J 2008;204:29-32.  Back to cited text no. 5
    
6.San Miguel SM, Opperman LA, Allen EP, Svoboda KK. Use of antioxidants in oral healthcare. Compend Contin Educ Dent 2011;32:e25-8.  Back to cited text no. 6
    

 
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Ranjan Malhotra




 

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