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ORIGINAL ARTICLE
Year : 2012  |  Volume : 3  |  Issue : 1  |  Page : 19-23

Efficacy of ibuprofen and paracetamol and diclofenac sodium and paracetamol combination on postoperative pain following root canal preparation in a randomized placebo-controlled study


Department of Conservative Dentistry and Endodontics, National Dental College & Hospital, Dera Bassi, India

Correspondence Address:
Nisha Kaler
Department of Conservative Dentistry and Endodontics, National Dental College & Hospital, Dera Bassi, Mohali, Punjab
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0976-6944.101671

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Aim: To compare the efficacy of two different oral analgesic combinations on postoperative pain following root canal preparation in teeth with irreversible pulpitis. Materials and Methods: In this in-vivo study, 30 patients who were diagnosed with irreversible pulpitis in anteriors or premolars, having moderate to severe pain were divided randomly into three groups of 10 patients each. The two experimental groups received a single dose of either ibuprofen or paracetamol or diclofenac sodium and paracetamol combination while the control group received placebo medication, immediately after the first appointment where the pulp was extirpated and canals were fully prepared. The intensity of pain was recorded preoperatively and at 6hrs, 12hrs and 24hrs postoperatively using both Visual Analogue Scale (VAS) and Verbal Descriptor Scale (VDS). The data was analyzed statistically. Result: At 6hrs, 12hrs and 24hrs postoperatively, the intensity of pain was significantly lower in experimental groups than in placebo group. Diclofenac sodium and paracetamol combination was more effective than ibuprofen and paracetamol combination in relieving postoperative pain. Conclusion: A single oral dose of diclofenac sodium and paracetamol and ibuprofen and paracetamol combination reduced postoperative pain following pulpectomy and root canal preparation of teeth with irreversible pulpitis.


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